(Senior) Manager, Medical Science Liaison (MSL)

Sironax is seeking a highly motivated and scientifically rigorous (Senior) Manager, Medical Science Liaison (MSL) to serve as a key field-based scientific expert supporting the company’s clinical-stage neurology and neurodegenerative disease portfolio, including programs in ALS. Reporting to the VP, Head of Clinical Research, China & APAC, this role will establish and maintain trusted scientific relationships with key opinion leaders (KOLs), investigators, academic researchers, advocacy organizations, and healthcare professionals. This individual will serve as a critical bridge between the external scientific community and Sironax’s internal team, contributing to scientific strategy, providing clinical insights, supporting clinical trial initiatives, and helping establish Sironax’s medical affairs capabilities in preparation for future clinical development and product commercialization.

Scientific Exchange & KOL Engagement

• Develop and maintain strategic relationships with KOLs, investigators, treatment centers, and healthcare professionals and facilitate bidirectional scientific exchange between external experts and internal stakeholders.
• Serve as the primary field-based scientific expert on Sironax’s pipeline, clinical programs, disease-state knowledge, and emerging scientific data.
• Conduct high-quality, compliant scientific discussions regarding disease pathophysiology, treatment landscapes, unmet medical needs, and clinical research.

Clinical Trial Support

• Collaborate with Clinical Operations by identifying potential trial sites and investigators, and gathering investigator feedback regarding protocol design, endpoint selection, patient recruitment, and operational execution.
• Participate in investigator meetings, advisory boards, and scientific workshops.

Medical Insights Generation

• Collect, analyze, and communicate field insights regarding the competitive landscape, emerging scientific trends, treatment patterns, unmet patient needs, clinical research trends and clinical practice evolution.
• Support due diligence activities and scientific assessments with potential business development opportunities.
• The Competitive intelligence tracking, slides deck making/presentation on TA, supporting clinical research team on scientific desk research, etc.

Medical Affairs Strategy

• Partner with Sironax leadership to execute field engagement strategies.
• Support development of medical communication materials, scientific and investor slide decks, training content, and evidence summaries.
• Lead scientific congress planning and execution , representing Sironax at major scientific and medical congresses.
• Participate in advisory board planning and management.
• Contribute to publication planning and scientific communication initiatives.
• Facilitate KOL meetings and scientific discussions during congresses.

Compliance

• Ensure all activities are conducted in accordance with applicable Chinese regulations (e.g., NMPA requirements, Drug Administration Law, GCP), OIG guidance, PhRMA Code, Sironax SOPs, and applicable global regulations (with Chinese regulations taking precedence).
• Maintain accurate documentation and reporting of field medical activities.

• Master and above degree of scientific or clinical degree is required
• Minimum 5 years of biotechnology, pharmaceutical, academic, or clinical research experience, with at least 3 years as a MSL in a clinical or commercial stage biotech or pharmaceutcal company.
• Experience in neuroscience, neurodegenerative diseases, neuromuscular disorders or autoimmunology TA are strongly preferred.
• Demonstrated success engaging KOLs and academic investigators.
• Experience supporting investigator-sponsored studies and clinical trial initiatives preferred.
• Exceptional scientific presentation skills, with the ability to translate complex scientific information into clear and actionable insights.
• Strong written communication and scientific storytelling capabilities.
• Ability to operate effectively in a fast-paced, entrepreneurial setting.
• Global experience supporting programs across North America, Europe, and Asia-Pacific regions preferred.

• Travel to investigator sites, academic medical centers, and advocacy events throughout China and internationally as needed.